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Destination

Panama Canal cruises from Los Angeles

One-way voyages, mostly 14 to 20 nights, that end in Florida, with a few going on to Boston or New York. They follow the coast of Mexico and Central America, pass through the canal and finish on the other side of the country, so the flight home is part of the plan. Princess sails the most of them.

Our Panama Canal guide covers which voyages go all the way through and where they end.

There are 25 such sailings on the board, running 12 to 44 nights, operated by Princess Cruises, Regent Seven Seas Cruises, Seabourn, Celebrity Cruises, Norwegian Cruise Line, Virgin Voyages, Oceania Cruises, Carnival Cruise Line, and Cunard aboard Crown Princess, Island Princess, Seven Seas Grandeur, Seven Seas Prestige, Seabourn Quest, Celebrity Summit, Coral Princess, Norwegian Joy, Star Princess, Norwegian Bliss, Emerald Princess, Brilliant Lady, Oceania Sonata, Norwegian Encore, Carnival Luminosa, and Queen Elizabeth. The lowest recorded starting fare is $1,199 per person, on the Sun, Oct 24, 2027 departure.

Ports of call

Panama Canal21 Puntarenas (Costa Rica)19 Puerto Quetzal (Guatemala)17 Puerto Vallarta (Mexico)13 Aruba13 Cabo San Lucas (Mexico)13 Fuerte Amador (Panama)12 Huatulco (Mexico)11 Cartagena (Colombia)11 Acapulco (Mexico)7 Puerto Chiapas (Mexico)5 Panama City (Panama)5 Grand Cayman (Cayman Islands)4 Puerto Caldera (Costa Rica)4 Miami (Florida)4 Mazatlan (Mexico)3 Falmouth (Jamaica)2 Great Stirrup Cay (Bahamas)2 Ensenada (Mexico)2 Curaçao1 Grand Turk (Turks and Caicos)1 Ocho Rios (Jamaica)1 Philipsburg (St. Maarten)1 Fort-de-France (Martinique)1 St. Lucia1 Grenada1 San Juan (Puerto Rico)1 St. Thomas (U.S. Virgin Islands)1 Basseterre (St. Kitts)1 Pointe-a-Pitre (Guadeloupe)1 Tortola (British Virgin Islands)1 Cozumel (Mexico)1 Roatan (Honduras)1 Harvest Caye (Belize)1 Costa Maya (Mexico)1
Schedule last updated · 25 departures listed · Dates can change. Verify with the cruise line before booking.

Your Panama Canal options

All routes

The 25 departures below run 18 different routes, cheapest per night first.

Distinct itineraries available, cheapest per night first
ItineraryNightsFrom
18-Night Panama Canal Eastbound

Calls at Puerto Vallarta (Mexico) · Puerto Quetzal (Guatemala) · Puntarenas (Costa Rica) · Panama Canal · Cartagena (Colombia) · Grand Turk (Turks and Caicos)

Ends in Boston (Massachusetts)

Next on Sat, Sep 18, 2027

18$1,262$70 a night
16-Night Transcanal

Calls at Puerto Vallarta (Mexico) · Huatulco (Mexico) · Puerto Chiapas (Mexico) · Puntarenas (Costa Rica) · Fuerte Amador (Panama) · Panama Canal · Curaçao

Ends in Fort Lauderdale (Florida)

Next on Thu, Dec 3, 2026

16$1,199$75 a night
14-Night Panama Canal

Calls at Cabo San Lucas (Mexico) · Puntarenas (Costa Rica) · Panama Canal · Cartagena (Colombia)

Ends in Miami (Florida)

Next on Thu, Apr 6, 2028

14$1,204$86 a night
18-Night Transcanal

Calls at Puerto Vallarta (Mexico) · Huatulco (Mexico) · Puerto Quetzal (Guatemala) · Puntarenas (Costa Rica) · Fuerte Amador (Panama) · Panama Canal · Aruba

Ends in New York (New York)

Next on Mon, Sep 27, 2027

18$1,849$103 a night
17-Night Panama Canal: Los Angeles to Miami

Calls at Cabo San Lucas (Mexico) · Puerto Quetzal (Guatemala) · Puntarenas (Costa Rica) · Panama City (Panama) · Cartagena (Colombia)

Ends in Miami (Florida)

Next on Sat, Nov 27, 2027

17$2,023$119 a night
20-Night Repositioning

Calls at Cabo San Lucas (Mexico) · Acapulco (Mexico) · Puerto Quetzal (Guatemala) · Puerto Caldera (Costa Rica) · Panama City (Panama) · Panama Canal · Cartagena (Colombia) · Falmouth (Jamaica) · Great Stirrup Cay (Bahamas) · Miami (Florida)

Ends in New York (New York)

Next on Tue, Oct 19, 2027

20$2,419$121 a night
15-Night Repositioning

Calls at Cabo San Lucas (Mexico) · Acapulco (Mexico) · Puerto Quetzal (Guatemala) · Puerto Caldera (Costa Rica) · Panama City (Panama) · Panama Canal · Cartagena (Colombia)

Ends in Miami (Florida)

Next on Sun, Jan 9, 2028

15$1,829$122 a night
17-Night Repositioning

Calls at Cabo San Lucas (Mexico) · Acapulco (Mexico) · Puerto Quetzal (Guatemala) · Puerto Caldera (Costa Rica) · Panama City (Panama) · Panama Canal · Cartagena (Colombia) · Falmouth (Jamaica) · Great Stirrup Cay (Bahamas)

Ends in Miami (Florida)

Next on Tue, Oct 19, 2027

17$2,159$127 a night

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, checked . Fares change often, so check the current price before you book.

Every departure by date

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By month

December 2026 2 January 2027 1 February 2027 1 March 2027 1 April 2027 1 May 2027 1 September 2027 3 October 2027 5 November 2027 1 December 2027 1 January 2028 4 March 2028 1 April 2028 2 October 2028 1

Other destinations from Los Angeles

Baja and Ensenada 375 sailings · from $193 Mexican Riviera 193 sailings · from $298.75 Hawaii 30 sailings · from $1,074 Pacific Coast 36 sailings · from $339 Alaska 7 sailings · from $1,524 South Pacific 9 sailings · from $2,199 World cruises and other long voyages 21 sailings · from $1,244

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, checked . Fares change often, so check the current price before you book.

Panama Canal from Los Angeles: questions

How many Panama Canal cruises leave Los Angeles?
25 Panama Canal cruises leave Los Angeles, across 14 months, on 16 ships from Princess Cruises, Regent Seven Seas Cruises, Seabourn, Celebrity Cruises, Norwegian Cruise Line, Virgin Voyages, Oceania Cruises, Carnival Cruise Line, and Cunard.

How long are Panama Canal cruises from Los Angeles?
From 12 to 44 nights. The most common length is 16 nights, on 13 of the 25 sailings.

Which ports do Panama Canal cruises from Los Angeles call at?
Most commonly Panama Canal (21 sailings), Puntarenas (19 sailings), Puerto Quetzal (17 sailings), Puerto Vallarta (13 sailings), and Aruba (13 sailings).